9-(Boc-amino)nonanoic acid functions as a PROTAC linker, featuring an alkane chain that contains a terminal carboxylic acid and a Boc-protected amino group. This compound is instrumental in the synthesis of PROTACs, as its carboxylic acid can efficiently react with primary amines in the presence of coupling agents, such as EDC or HATU, to yield stable amide bonds. The Boc protecting group can be removed under mild acidic conditions, resulting in the formation of the free amine, facilitating subsequent chemical modifications.
9-(Boc-amino)nonanoic acid functions as a PROTAC linker, featuring an alkane chain that contains a terminal carboxylic acid and a Boc-protected amino group. This compound is instrumental in the synthesis of PROTACs, as its carboxylic acid can efficiently react with primary amines in the presence of coupling agents, such as EDC or HATU, to yield stable amide bonds. The Boc protecting group can be removed under mild acidic conditions, resulting in the formation of the free amine, facilitating subsequent chemical modifications.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
