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- Hua Xu, .et al. Preclinical Study Using ABT263 to Increase Enzalutamide Sensitivity to Suppress Prostate Cancer Progression Via Targeting BCL2/ROS/USP26 Axis Through Altering ARv7 Protein Degradation, Cancers (Basel), 2020, Apr; 12(4): 831 PMID: 32235588
- R Kasi, .et al. Melatonin Induces Apoptosis and Inhibits the Proliferation of Cancer Cells via Reactive Oxygen Species-mediated MAPK and mTOR Pathways, Clinical Cancer Drugs, 2020, 2019, 7(1): 44 - 56
Biological Activity
Acetylcysteine is a pharmaceutical drug and nutritional supplement used primarily as a mucolytic agent and in the management of paracetamol (acetaminophen) overdose. Oral acetylcysteine is also used for the prevention of radiocontrast-induced nephropathy (a form of acute renal failure).
| In vitro | DMSO | 32 mg/mL (196.08 mM) | |
| Water | 32 mg/mL (196.08 mM) | ||
| Ethanol | 32 mg/mL (196.08 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 61.27 mL | 306.37 mL | 612.75 mL |
| 0.5 mM | 12.25 mL | 61.27 mL | 122.55 mL |
| 1 mM | 6.13 mL | 30.64 mL | 61.27 mL |
| 5 mM | 1.23 mL | 6.13 mL | 12.25 mL |
*The above data is based on the productmolecular weight 163.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10032 |
|---|---|
| CAS No. | 616-91-1 |
| Formula | C5H9NO3S |
| M. Wt | 163.2 |
| Purity | >98% |
| Synonyms | N-acetylcysteine, N-acetyl-L-cysteine, NAC, Acetadote |
| SMILES | CC(=O)N[[email protected]@H](CS)C(=O)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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