Aciclovir (Acyclovir)

Catalog No.: A10037

Aciclovir (Acyclovir)

Aciclovir (Acyclovir) Chemical Structure

CAS NO. 59277-89-3

Aciclovir is an antiviral agent primarily used for the treatment of herpes simplex virus infections, as well as in the treatment of varicella zoster (chickenpox) and herpes zoster (shingles). It was seen as the start of a new era in antiviral therapy, as it is extremely selective and low in cytotoxicity.

Availability: In stock

Package Price Qty
50 mg
$50.00
100 mg
$70.00
200 mg
$95.00
500 mg
$130.00
10mM * 1mL in DMSO
$61.00
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  • Takashi Azuma, .et al. Removal of pharmaceuticals in water by introduction of ozonated microbubbles, SEP PURIF TECHNOL, 2019, Apr; 212: 483-489
  • Azuma T, .et al. Distribution of six anticancer drugs and a variety of other pharmaceuticals, and their sorption onto sediments, in an urban Japanese river, Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 PMID: 28660504
  • Azuma T, .et al. Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents, Sci Total Environ, 2016, Apr 1;548-549:189-197 PMID: 26802347

Biological Activity

Aciclovir is an antiviral agent primarily used for the treatment of herpes simplex virus infections, as well as in the treatment of varicella zoster (chickenpox) and herpes zoster (shingles). It was seen as the start of a new era in antiviral therapy, as it is extremely selective and low in cytotoxicity.
Targets
HSV
In vitro DMSO 45 mg/mL (199.82 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 44.4 mL 222.02 mL 444.05 mL
0.5 mM 8.88 mL 44.4 mL 88.81 mL
1 mM 4.44 mL 22.2 mL 44.4 mL
5 mM 0.89 mL 4.44 mL 8.88 mL

*The above data is based on the productmolecular weight 225.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10037
M. Wt 225.2
Formula C8H11N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 59277-89-3
Synonyms Acycloguanosine, Zovirax, ACV
SMILES C1=NC2=C(N1COCCO)NC(=NC2=O)N

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