ACY-738

Catalog No.: A15934
HDAC6 inhibitor
ACY-738 is a potent and selective HDAC6 inhibitor with improved brain bioavailability. ACY-738 inhibits HDAC6 with low nanomolar potency and a selectivity of 60- to 1500-fold over class I HDACs.
Grouped product items
Size Price Stock Qty
1mg
$35.00
In stock
2mg
$50.00
In stock
5mg
$90.00
In stock
10mg
$170.00
In stock
25mg
$290.00
In stock
50mg
$480.00
In stock
100mg
$640.00
In stock
10mM * 1mL in DMSO
$100.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Adooq's ACY-738 has been cited by 2 publications
  • Dao Xu, .et al. , Immunohorizons, 2024, Sep 1;8(9):668-678 PMID: 39259207
  • Guang Bai, .et al. , Epigenetics of Chronic Pain, 2019, Pages 1-48
Biological Activity
DescriptionACY-738 is a potent and selective HDAC6 inhibitor with improved brain bioavailability. ACY-738 inhibits HDAC6 with low nanomolar potency and a selectivity of 60- to 1500-fold over class I HDACs.
Targets
TargetValue
Cell Research
Cell LineTypeValueDescriptionReferences
Product Information
Catalog NumA15934
FormulaC14H14N4O2
Molecular Weight270.29
CAS Number1375465-91-0
SMILESO=C(C1=CN=C(NC2(C3=CC=CC=C3)CC2)N=C1)NO
SynonymsACY 738, ACY738
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO46 mg/mL (170.18 mM)
WaterInsoluble
Ethanol1 mg/mL (3.69 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM37 mL184.99 mL369.97 mL
0.5 mM7.4 mL37 mL73.99 mL
1 mM3.7 mL18.5 mL37 mL
5 mM0.74 mL3.7 mL7.4 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

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