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Ala0-Actagardine

Catalog No.: A47785
Antibiotic
Ala0-Actagardine is a lantibiotic that targets bacterial cell membranes, derived from the cultures of Actinoplanes liguriae ATCC 31048. This compound exhibits potent antibacterial activity against a range of Gram-positive pathogens, making it valuable for research in antibiotic resistance and pathogen sensitivity studies. Its unique mechanism of action provides insights into peptide antibiotics and their potential therapeutic applications in infectious disease treatment.
Ala0-Actagardine 223465-14-3 Antibiotic
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAla0-Actagardine is a lantibiotic that targets bacterial cell membranes, derived from the cultures of Actinoplanes liguriae ATCC 31048. This compound exhibits potent antibacterial activity against a range of Gram-positive pathogens, making it valuable for research in antibiotic resistance and pathogen sensitivity studies. Its unique mechanism of action provides insights into peptide antibiotics and their potential therapeutic applications in infectious disease treatment.
Product Information
Catalog NumA47785
FormulaC84H129N21O25S4
Molecular Weight1961.31
CAS Number223465-14-3
SMILESO=C(N[C@H](C(N[C@@H](CSC[C@H]1NC([C@@H](N)C)=O)C(N[C@H]([C@@H](SC[C@](C(NCC(N[C@@]([C@@H]([S](C[C@H]2C(O)=O)=O)C)([H])C(N[C@H]3C(C)C)=O)=O)=O)([H])NC([C@@H](NC4=O)CCC(O)=O)=O)C)C(N[C@H](C(N[C@@]([C@@H](SC[C@](C(N[C@H](C(N2)=O)C)=O)([H])NC([C@](NC3=O)([H])[C@@H](C)CC)=O)C)([H])C(N[C@@]4([H])[C@@H](C)CC)=O)=O)CC(C)C)=O)=O)=O)C(C)C)[C@@H](NC(CNC([C@@H](NC1=O)CO)=O)=O)CC5=CNC6=CC=CC=C56
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Microbiology > Antifection > Antibiotic