Ald-C2-PEG4-azide serves as a PEG-based PROTAC linker, facilitating the synthesis of PROTAC compounds. This compound features an azide functional group enabling its participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups, making it a versatile tool for bioconjugation and targeted protein degradation studies.
Ald-C2-PEG4-azide serves as a PEG-based PROTAC linker, facilitating the synthesis of PROTAC compounds. This compound features an azide functional group enabling its participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups, making it a versatile tool for bioconjugation and targeted protein degradation studies.
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