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Biological Activity
Aliskiren D6 Hydrochloride (CGP 60536 D6 Hydrochloride) is is deuterium labeled Aliskiren, which is a direct renin inhibitor with IC50 of 1.5 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.83 mL | 84.14 mL | 168.28 mL |
| 0.5 mM | 3.37 mL | 16.83 mL | 33.66 mL |
| 1 mM | 1.68 mL | 8.41 mL | 16.83 mL |
| 5 mM | 0.34 mL | 1.68 mL | 3.37 mL |
*The above data is based on the productmolecular weight 594.26. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21913 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1246815-96-2 |
| Formula | C30H48D6ClN3O6 |
| M. Wt | 594.26 |
| Purity | >98% |
| Synonyms | CGP 60536 D6 Hydrochloride; CGP60536B D6 Hydrochloride; SPP 100 D6 Hydrochloride |
| SMILES | O=C(NCC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C(N)=O)[[email protected]](C(C)C)C[[email protected]](O)[[email protected]@H](N)C[[email protected]@H](C(C)C)CC1=CC(OCCCOC)=C(OC)C=C1.[H]Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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