Aliskiren hemifumarate

Name: Aliskiren hemifumarate
Brand: Adooq Bioscience
SKU: A11123
Rating: 100 (268 reviews)

Catalog No.: A11123

renin inhibitor

Aliskiren hemifumarate Chemical Structure

CAS NO. 173334-58-2

Aliskiren hemifumarate is a hemifumarate salt form of Aliskiren, which is a direct renin inhibitor approved for the treatment of essential hypertension.

Availability: In stock

Package	Price	Qty
2 mg	$20.00
5 mg	$30.00
10 mg	$50.00
50 mg	$130.00
10mM * 1mL in DMSO	$80.00
Custom Size	Get quote

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Biological Activity

Aliskiren hemifumarate is a hemifumarate salt form of Aliskiren, which is a direct renin inhibitor approved for the treatment of essential hypertension.

Targets

Renin
1.5 nM

Solubility *

In vitro	DMSO	89 mg/mL (145.94 mM)
	Water	89 mg/mL (145.94 mM)
	Ethanol	89 mg/mL (145.94 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	16.4 mL	81.99 mL	163.99 mL
0.5 mM	3.28 mL	16.4 mL	32.8 mL
1 mM	1.64 mL	8.2 mL	16.4 mL
5 mM	0.33 mL	1.64 mL	3.28 mL

*The above data is based on the productmolecular weight 609.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num	A11123
Actions	Inhibitor
CAS No.	173334-58-2
Formula	C30H53N3O6.1/2C4H4O4
M. Wt	609.8
Purity	>98%
SMILES	CC(C)[[email protected]@H](CC1=CC(=C(C=C1)OC)OCCCOC)C[[email protected]@H]([[email protected]](C[[email protected]@H](C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N.CC(C)[[email protected]@H](CC1=CC(=C(C=C1)OC)OCCCOC)C[[email protected]@H]([[email protected]](C[[email protected]@H](C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N.C(=C/C(=O)O)\C(=O)O
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.