Alpelisib hydrochloride

Catalog No.: A21794

PI3Kα inhibitor

Alpelisib hydrochloride

Alpelisib hydrochloride Chemical Structure

CAS NO. 1584128-91-5

Alpelisib hydrochloride (BYL-719 hydrochloride) is a potent, orally active, and selective PI3Kα inhibitor with IC50s of 5 nM, 250 nM, 290 nM and 1200 nM for p110α, p110γ, p110δ, and p110β, respectively.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

Alpelisib hydrochloride (BYL-719 hydrochloride) is a potent, orally active, and selective PI3Kα inhibitor with IC50s of 5 nM, 250 nM, 290 nM and 1200 nM for p110α, p110γ, p110δ, and p110β, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.92 mL 104.62 mL 209.24 mL
0.5 mM 4.18 mL 20.92 mL 41.85 mL
1 mM 2.09 mL 10.46 mL 20.92 mL
5 mM 0.42 mL 2.09 mL 4.18 mL

*The above data is based on the productmolecular weight 477.93. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21794
Actions Inhibitor
M. Wt 477.93
Formula C19H23ClF3N5O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1584128-91-5
Synonyms BYL-719 hydrochloride, BYL 719, BYL719
SMILES CC(N=C(S1)NC(N2CCC[[email protected]]2C(N)=O)=O)=C1C3=CC(C(C)(C(F)(F)F)C)=NC=C3.Cl

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