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BYL719 (Alpelisib)


PI3K Inhibitor

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Catalog No. A11328

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
BYL719 5mg A11328-5

Regular Price: €57.00

Special Price: €51.30

BYL719 10mg A11328-10

Regular Price: €85.50

Special Price: €76.95

BYL719 25mg A11328-25

Regular Price: €114.00

Special Price: €102.60

BYL719 50mg A11328-50

Regular Price: €133.00

Special Price: €119.70

BYL719 10mM * 1mL in DMSO A11328-10mM-D

Regular Price: €57.00

Special Price: €51.30

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

BLY719 is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity.

BYL719 (Alpelisib)

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Publications citing Adooq Products
BYL719 (Alpelisib) Citations (2)
  • J Wei, .et al. Profiling the surface proteome identifies actionable biology for TSC1 mutant cells beyond mTORC1 signaling, bioRxiv, 2018, 2018
  • Pridham KJ, .et al. PIK3CB/p110β is a selective survival factor for glioblastoma, Neuro Oncol, 2018, Mar 27;20(4):494-505 PMID: 29016844

Chemical Information

Catalog Num A11328
Actions Inhibitor
M. Wt 441.5
Formula C19H22F3N5O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1217486-61-7
Synonyms BYL-719
SMILES CC1=C(SC(=N1)NC(=O)N2CCC[[email protected]]2C(=O)N)C3=CC(=NC=C3)C(C)(C)C(F)(F)F

Biological Activity

BLY719 is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity.
PI3Kα (Cell-free assay)
5 nM


Solubility (25°C) * In vitro DMSO 88 mg/mL (199.33 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (4.53 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.65 mL 113.25 mL 226.5mL
0.5 mM 4.53 mL 22.65 mL 45.3 mL
1 mM 2.27 mL 11.33 mL 22.65 mL
5 mM 0.45 mL 2.27 mL 4.53 mL

*The above data is based on the productmolecular weight 441.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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