BYL719 (Alpelisib)

BLY719 is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity.
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BYL719 5mg
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BYL719 10mg
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BYL719 25mg
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BYL719 50mg
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BYL719 10mM * 1mL in DMSO
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's BYL719 (Alpelisib) has been cited by 4 publications
  • Elaheh S Abutorabi, .et al. , Mol Biol Rep, 2023, May;50(5):4073-4082 PMID: 36877344
  • Lisann Pelzl, .et al. , J Thromb Haemost, 2022, Feb;20(2):387-398 PMID: 34752677
  • J Wei, .et al. , bioRxiv, 2018, 2018
  • Pridham KJ, .et al. , Neuro Oncol, 2018, Mar 27;20(4):494-505 PMID: 29016844
  • Biological Activity
    Discription BLY719 is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity.
    Target Value
    Product Information
    Catalog Num A11328
    Formula C19H22F3N5O2S
    Molecular Weight 441.5
    CAS Number 1217486-61-7
    SMILES CC1=C(SC(=N1)NC(=O)N2CCC[C@H]2C(=O)N)C3=CC(=NC=C3)C(C)(C)C(F)(F)F
    Synonyms BYL-719

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 77 mg/mL (174.41 mM)
    Water Insoluble
    Ethanol 2 mg/mL (4.53 mM)
    In vivo 5%DMSO+40%PEG300+5%Tween80+50%ddH2O 4.1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.65 mL 113.25 mL 226.5 mL
    0.5 mM 4.53 mL 22.65 mL 45.3 mL
    1 mM 2.27 mL 11.33 mL 22.65 mL
    5 mM 0.45 mL 2.27 mL 4.53 mL
    Useful Calculator

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    Calculate the dilution required to prepare a stock solution.
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