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- J Wei,et al. Profiling the surface proteome identifies actionable biology for TSC1 mutant cells beyond mTORC1 signaling, bioRxiv, 2018, 2018
- Pridham KJ,et al. PIK3CB/p110汕 is a selective survival factor for glioblastoma, Neuro Oncol, 2018, Mar 27;20(4):494-505 29016844
|Storage||at -20°C 3 years Powder|
|SMILES code||CC1=C(SC(=N1)NC(=O)N2CCC[[email protected]]2C(=O)N)C3=CC(=NC=C3)C(C)(C)C(F)(F)F|
|BLY719 is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity.|
|Solubility (25°C) *||In vitro||DMSO||88 mg/mL (199.33 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||2 mg/mL (4.53 mM)|
|In vivo||30% PEG400/0.5% Tween80/5% propylene glycol||30 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||22.65 mL||113.25 mL||226.5mL|
|0.5 mM||4.53 mL||22.65 mL||45.3 mL|
|1 mM||2.27 mL||11.33 mL||22.65 mL|
|5 mM||0.45 mL||2.27 mL||4.53 mL|
*The above data is based on the productmolecular weight 441.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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