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ALS-8112 is a potent and selective respiratory syncytial virus (RSV) polymerase inhibitor. The 5'-triphosphate form of ALS-8112 inhibits RSV polymerase with an IC50 of 0.02 μM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 34.05 mL | 170.25 mL | 340.51 mL |
| 0.5 mM | 6.81 mL | 34.05 mL | 68.1 mL |
| 1 mM | 3.41 mL | 17.03 mL | 34.05 mL |
| 5 mM | 0.68 mL | 3.41 mL | 6.81 mL |
*The above data is based on the productmolecular weight 293.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21374 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1445379-92-9 |
| Formula | C10H13ClFN3O4 |
| M. Wt | 293.68 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | ALS8112, ALS 8112 |
| SMILES | OC[[email protected]]1(CCl)[[email protected]@H](O)[[email protected]@H](F)[[email protected]](N2C(N=C(N)C=C2)=O)O1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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