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Plerixafor is an immunostimulant used to multiply hematopoietic stem cells and it is a chemokine receptor-4 antagonist for mobilization of hematopoietic stem cells for transplantation.
Targets
| CXCL12-mediated chemotaxis (Cell-free assay) | CXCR4 (Cell-free assay) | |||
| 5.7 nM | 44 nM |
| In vitro (25°C) | DMSO | <1 mg/mL (<1 mM) | |
| Water | 3 mg/mL heating (5.96 mM) | ||
| Ethanol | 100 mg/mL (198.89 mM) | ||
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 30 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.89 mL | 99.45 mL | 198.89 mL |
| 0.5 mM | 3.98 mL | 19.89 mL | 39.78 mL |
| 1 mM | 1.99 mL | 9.94 mL | 19.89 mL |
| 5 mM | 0.4 mL | 1.99 mL | 3.98 mL |
*The above data is based on the productmolecular weight 502.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13074 |
|---|---|
| Actions | Antagonist |
| M. Wt | 502.78 |
| Formula | C28H54N8 |
| Solubility | DMSO <1 mg/mL (<1 mM) ; Water 6 mg/mL (11 mM) ; Ethanol 100 mg/mL (198 mM) |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 110078-46-1 |
| SMILES | C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3 |
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