Biological Activity
Amorolfine hydrochloride, is a morpholine antifungal reagent that inhibits D14 reductase and D7-D8 isomerase, which depletes ergosterol and causes ignosterol to accumulate in the fungal cytoplasmic cell membranes.
In vitro | DMSO | 28 mg/mL (79.1 mM) | |
Water | 9 mg/mL (25.42 mM) | ||
Ethanol | 71 mg/mL (200.58 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 28.25 mL | 141.24 mL | 282.49 mL |
0.5 mM | 5.65 mL | 28.25 mL | 56.5 mL |
1 mM | 2.82 mL | 14.12 mL | 28.25 mL |
5 mM | 0.56 mL | 2.82 mL | 5.65 mL |
*The above data is based on the productmolecular weight 354.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A10072 |
---|---|
M. Wt | 354.0 |
Formula | C21H36ClNO |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 78613-38-4 |
Synonyms | Amorolfin, Curanail, Loceryl, Locetar, Odenil |
SMILES | CCC(C)(C)C1=CC=C(C=C1)CC(C)CN2C[[email protected]](O[[email protected]](C2)C)C.Cl |
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