AMPK activator 8 is a potent activator of AMP-activated protein kinase (AMPK), demonstrating EC50 values of 11, 27, 4, 2, and 4 nM for various AMPK isoforms: rAMPK α1β1γ1, rAMPK α2β1γ1, rAMPK α1β2γ1, rAMPK α2β2γ1, and rAMPK α2β2γ3. This compound is particularly valuable for studying metabolic disorders, specifically type 2 diabetes, by enhancing AMPK activity and modulating glucose metabolism. Its high specificity and efficacy make it an important tool for researchers exploring AMPK-related pathways and therapeutic interventions.
AMPK activator 8 is a potent activator of AMP-activated protein kinase (AMPK), demonstrating EC50 values of 11, 27, 4, 2, and 4 nM for various AMPK isoforms: rAMPK α1β1γ1, rAMPK α2β1γ1, rAMPK α1β2γ1, rAMPK α2β2γ1, and rAMPK α2β2γ3. This compound is particularly valuable for studying metabolic disorders, specifically type 2 diabetes, by enhancing AMPK activity and modulating glucose metabolism. Its high specificity and efficacy make it an important tool for researchers exploring AMPK-related pathways and therapeutic interventions.
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