Anticancer agent 139 (Compound 6h) primarily targets tubulin through π-cationic interactions with the lysine residue Lys352, demonstrating strong anticancer activity. This compound exhibits significant efficacy against various cancer cell lines, including SNB-19, OVCAR-8, and NCI-H40, with proliferation growth inhibition (PGI) values of 86.61, 85.26, and 75.99, respectively. Additionally, anticancer agent 139 shows moderate activity against HOP-62, SNB-75, and others, making it a valuable tool for cancer research and drug discovery applications.
Anticancer agent 139 (Compound 6h) primarily targets tubulin through π-cationic interactions with the lysine residue Lys352, demonstrating strong anticancer activity. This compound exhibits significant efficacy against various cancer cell lines, including SNB-19, OVCAR-8, and NCI-H40, with proliferation growth inhibition (PGI) values of 86.61, 85.26, and 75.99, respectively. Additionally, anticancer agent 139 shows moderate activity against HOP-62, SNB-75, and others, making it a valuable tool for cancer research and drug discovery applications.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
