APX-115

Catalog No.: A18737

Nox inhibitor

APX-115

APX-115 Chemical Structure

CAS NO. 1395946-75-4

APX-115 (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. APX-115 effectively prevents kidney injury.

Availability: In stock

Package Price Qty
1 mg
$300.00
5 mg
$1,200.00
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Biological Activity

APX-115 (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. APX-115 effectively prevents kidney injury.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.67 mL 158.33 mL 316.66 mL
0.5 mM 6.33 mL 31.67 mL 63.33 mL
1 mM 3.17 mL 15.83 mL 31.67 mL
5 mM 0.63 mL 3.17 mL 6.33 mL

*The above data is based on the productmolecular weight 315.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18737
Actions Inhibitor
M. Wt 315.8
Formula C17H18ClN3O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1395946-75-4
Synonyms APX 115, APX115
SMILES OC1=C(CCC)C(C2=CC=CC=C2)=NN1C3=NC=CC=C3.Cl

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