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Biological Activity
AR234960, a non-peptide MAS (a G protein-coupled receptor) agonist, increases both mRNA and protein levels of CTGF via ERK1/2 signaling in HEK293-MAS cells and adult human cardiac fibroblasts.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18 mL | 89.99 mL | 179.98 mL |
| 0.5 mM | 3.6 mL | 18 mL | 36 mL |
| 1 mM | 1.8 mL | 9 mL | 18 mL |
| 5 mM | 0.36 mL | 1.8 mL | 3.6 mL |
*The above data is based on the productmolecular weight 555.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18858 |
|---|---|
| Actions | Agonist |
| CAS No. | 1436426-86-6 |
| Formula | C27H30FN5O5S |
| M. Wt | 555.63 |
| Purity | >98% |
| Synonyms | AR234960; AR 234960; AR-234960; GTPL7039; GTPL-7039; GTPL 7039. |
| SMILES | O=S(N1CC(CN2CCN(C3=NC=CC=C3)CC2)C(C4=CC=CC(F)=C4)C1)(C5=CC=C([N+]([O-])=O)C=C5OC)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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