AT7867 2HCl

Catalog No.: A15006

Akt inhibitor

AT7867 2HCl

AT7867 2HCl Chemical Structure

CAS NO. 1431697-86-7

AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively, little activity outside the AGC kinase family.

Availability: In stock

Package Price Qty
10 mg
$160.00
50 mg
$540.00
200 mg
$1,600.00
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Biological Activity

AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively, little activity outside the AGC kinase family.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.34 mL 121.72 mL 243.45 mL
0.5 mM 4.87 mL 24.34 mL 48.69 mL
1 mM 2.43 mL 12.17 mL 24.34 mL
5 mM 0.49 mL 2.43 mL 4.87 mL

*The above data is based on the productmolecular weight 410.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15006
Actions Inhibitor
CAS No. 1431697-86-7
Formula C20H22Cl3N3
M. Wt 410.77
Purity >98%
Synonyms AT-7867 dihydrochloride, AT 7867 dihydrochloride
SMILES C1CNCCC1(C2=CC=C(C=C2)C3=CNN=C3)C4=CC=C(C=C4)Cl.Cl.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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