Awamycin

Catalog No.: A47568
Antitumor Antibiotic
Awamycin is an antitumor ansamycin antibiotic that primarily targets and inhibits Hsp90 (Heat shock protein 90). It exhibits potent cytotoxic activity against various cancer cell lines, making it a valuable tool for cancer research. Awamycin is utilized to study mechanisms of tumor growth and resistance, as well as to evaluate potential therapeutic strategies in oncology.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAwamycin is an antitumor ansamycin antibiotic that primarily targets and inhibits Hsp90 (Heat shock protein 90). It exhibits potent cytotoxic activity against various cancer cell lines, making it a valuable tool for cancer research. Awamycin is utilized to study mechanisms of tumor growth and resistance, as well as to evaluate potential therapeutic strategies in oncology.
Product Information
Catalog NumA47568
FormulaC38H49NO12S
Molecular Weight743.86
CAS Number87913-35-7
SMILESO=C(C(SC)=C1NC(/C(C)=C/C=C/[C@H]([C@H]([C@@H]([C@@H]([C@H]([C@H]([C@@H]([C@H]([C@@H](/C=C2\C)C)O)C)O)C(OC)=O)O)C)O)C)=O)C3=C(C(O)=C(C(OC)=C3C2=O)C)C1=O
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