AZ32

Catalog No.: A16814

ATM inhibitor

AZ32

AZ32 Chemical Structure

CAS NO. Not Available N/A

AZ32 is a specific inhibitor of the ATM kinase that possesses good BBB penetration in mouse with an IC50 value of <0.0062 μM for ATM enzyme. It shows adequate selectivity over ATR and also has high cell permeability.

Availability: In stock

Package Price Qty
5 mg
$140.00
10 mg
$220.00
50 mg
$600.00
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Biological Activity

AZ32 is a specific inhibitor of the ATM kinase that possesses good BBB penetration in mouse with an IC50 value of <0.0062 μM for ATM enzyme. It shows adequate selectivity over ATR and also has high cell permeability.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.45 mL 152.27 mL 304.53 mL
0.5 mM 6.09 mL 30.45 mL 60.91 mL
1 mM 3.05 mL 15.23 mL 30.45 mL
5 mM 0.61 mL 3.05 mL 6.09 mL

*The above data is based on the productmolecular weight 328.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16814
Actions Inhibitor
CAS No. Not Available N/A
Formula C20H16N4O
M. Wt 328.37
Solubility DMSO
Purity >98%
Synonyms AZ-32, AZ 32
SMILES O=C(NC)C(C=C1)=CC=C1C2=CN=C3C=NC(C4=CC=CC=C4)=CN32
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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