Biological Activity
AZ32 is a specific inhibitor of the ATM kinase that possesses good BBB penetration in mouse with an IC50 value of <0.0062 μM for ATM enzyme. It shows adequate selectivity over ATR and also has high cell permeability.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 30.45 mL | 152.27 mL | 304.53 mL |
0.5 mM | 6.09 mL | 30.45 mL | 60.91 mL |
1 mM | 3.05 mL | 15.23 mL | 30.45 mL |
5 mM | 0.61 mL | 3.05 mL | 6.09 mL |
*The above data is based on the productmolecular weight 328.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A16814 |
---|---|
Actions | Inhibitor |
M. Wt | 328.37 |
Formula | C20H16N4O |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | Not Available N/A |
Synonyms | AZ-32, AZ 32 |
SMILES | O=C(NC)C(C=C1)=CC=C1C2=CN=C3C=NC(C4=CC=CC=C4)=CN32 |
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy AZ32 | AZ32 Supplier | purchase | cost | manufacturer | order | distributor | buy Not Available N/A | Not Available N/A Supplier | purchase Not Available N/A | Not Available N/A cost | Not Available N/A manufacturer | order Not Available N/A | Not Available N/A distributor