AZD-6605 is a potent, reversible inhibitor targeting matrix metalloproteinases MMP2, MMP9, MMP12, and MMP13, exhibiting high selectivity. This compound was optimized for enhanced activity, solubility, and drug metabolism and pharmacokinetics (DMPK) properties by modifying the zinc hydroxide binding group found in traditional inhibitors. AZD-6605 is valuable for investigating the roles of these metalloproteinases in various biological processes and disease states, making it suitable for research applications in inflammation, cancer, and tissue remodeling studies.
AZD-6605 is a potent, reversible inhibitor targeting matrix metalloproteinases MMP2, MMP9, MMP12, and MMP13, exhibiting high selectivity. This compound was optimized for enhanced activity, solubility, and drug metabolism and pharmacokinetics (DMPK) properties by modifying the zinc hydroxide binding group found in traditional inhibitors. AZD-6605 is valuable for investigating the roles of these metalloproteinases in various biological processes and disease states, making it suitable for research applications in inflammation, cancer, and tissue remodeling studies.
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