AZD0156

Catalog No.: A16419

ATM inhibitor

AZD0156

AZD0156 Chemical Structure

CAS NO. 1821428-35-6

AZD0156 is a potent and selective inhibitors of ATM kinase, with potential chemo-/radio-sensitizing and antineoplastic activities.

Availability: In stock

Package Price Qty
5 mg
$60.00
10 mg
$100.00
50 mg
$300.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Yi-Ru Pan, .et al. ATM Inhibitor Suppresses Gemcitabine-Resistant BTC Growth in a Polymerase θ Deficiency-Dependent Manner, Biomolecules, 2020, Nov 9;10(11):1529 PMID: 33182492
  • >

Biological Activity

AZD0156 is a potent and selective inhibitors of ATM kinase, with potential chemo-/radio-sensitizing and antineoplastic activities.
In vitro DMSO Warmed: <1 mg/mL
Water Insoluble
Ethanol 2 mg/mL (4.33 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.67 mL 108.33 mL 216.66 mL
0.5 mM 4.33 mL 21.67 mL 43.33 mL
1 mM 2.17 mL 10.83 mL 21.67 mL
5 mM 0.43 mL 2.17 mL 4.33 mL

*The above data is based on the productmolecular weight 461.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16419
Actions Inhibitor
CAS No. 1821428-35-6
Formula C26H31N5O3
M. Wt 461.56
Solubility DMSO
Purity >98%
Synonyms AZD-0156, AZD 0156
SMILES O=C(N1C2CCOCC2)N(C)C3=C1C4=CC(C5=CC=C(OCCCN(C)C)N=C5)=CC=C4N=C3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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