Azido-PEG7-azide is a PEG-based linker designed for the synthesis of PROTACs, functioning through click chemistry. This compound features an azide group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) groups. Its versatile reactivity makes it a valuable tool for researchers in chemical biology and drug development.
Azido-PEG7-azide is a PEG-based linker designed for the synthesis of PROTACs, functioning through click chemistry. This compound features an azide group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) groups. Its versatile reactivity makes it a valuable tool for researchers in chemical biology and drug development.
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