Azido-PEG8-acid is a non-cleavable linker composed of eight polyethylene glycol (PEG) units, specifically designed for use in antibody-drug conjugates (ADCs) and PROTACs. It serves as a versatile click chemistry reagent due to its azide functionality, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it supports strain-promoted alkyne-azide cycloaddition (SPAAC) reactions when interacting with DBCO or BCN groups. This compound is essential for researchers focusing on the development of targeted therapeutic agents and protein degradation strategies.
Azido-PEG8-acid is a non-cleavable linker composed of eight polyethylene glycol (PEG) units, specifically designed for use in antibody-drug conjugates (ADCs) and PROTACs. It serves as a versatile click chemistry reagent due to its azide functionality, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it supports strain-promoted alkyne-azide cycloaddition (SPAAC) reactions when interacting with DBCO or BCN groups. This compound is essential for researchers focusing on the development of targeted therapeutic agents and protein degradation strategies.
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