Azido-PEG9-azide is a PEG-based PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). Featuring an azide group, it participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-bearing compounds. This reagent is instrumental in the development of targeted protein degradation strategies, promoting innovative research in drug discovery and protein regulation.
Azido-PEG9-azide is a PEG-based PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). Featuring an azide group, it participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-bearing compounds. This reagent is instrumental in the development of targeted protein degradation strategies, promoting innovative research in drug discovery and protein regulation.
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