Bay 11-7821
Bay 11-7821 is an irreversible inhibitor of TNF-α-stimulated IκBα phosphorylation.
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Adooq Products cited in reputable paper
Adooq's Bay 11-7821 has been cited by 4 publications
- Majid Momeny, .et al. , EMBO Mol Med, 2024, Jun 17 PMID: 38886591
- Ali Nasrollahzadeh, .et al. , Rep Biochem Mol Biol, 2022, Jan;10(4):602-613 PMID: 35291620
- Ali Nasrollahzadeh, .et al. , Life Sci, 2020, Jul 6;257:118060 PMID: 32645343
- Momeny M, .et al. , Int J Biochem Cell Biol, 2018, Jun;99:1-9 PMID: 29567488
Biological Activity
| Description | Bay 11-7821 is an irreversible inhibitor of TNF-α-stimulated IκBα phosphorylation. | |||||
|---|---|---|---|---|---|---|
| Targets |
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| Cell Research |
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Product Information
| Catalog Num | A11957 |
|---|---|
| Formula | C10H9NO2S |
| Molecular Weight | 207.25 |
| CAS Number | 19542-67-7 |
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)/C=C/C#N |
| Synonyms | Bay-11-7821, Bay 117821, Bay117821,Bay 11-7082, Bay-11-7082, Bay11-7082 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 39 mg/mL (188.17 mM) | |
| Water | Insoluble | ||
| Ethanol | 10 mg/mL (48.25 mM) | ||
| In vivo | 5% DMSO+corn oil | 7 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 48.25 mL | 241.25 mL | 482.51 mL |
| 0.5 mM | 9.65 mL | 48.25 mL | 96.5 mL |
| 1 mM | 4.83 mL | 24.13 mL | 48.25 mL |
| 5 mM | 0.97 mL | 4.83 mL | 9.65 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
