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Bay 11-7821


E2 ubiquitin conjugating enzyme inhibitor

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Catalog No. A11957

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Bay 11-7821 10mg A11957-10

Regular Price: $50.00

Special Price: $45.00

Bay 11-7821 25mg A11957-25

Regular Price: $90.00

Special Price: $81.00

Bay 11-7821 50mg A11957-50

Regular Price: $160.00

Special Price: $144.00

Bay 11-7821 100mg A11957-100

Regular Price: $280.00

Special Price: $252.00

Bay 11-7821 10mM * 1mL in DMSO A11957-10mM-D

Regular Price: $69.00

Special Price: $62.10

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Bay 11-7821 is an irreversible inhibitor of TNF-α-stimulated IκBα phosphorylation.

Bay 11-7821

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Publications citing Adooq Products
Bay 11-7821 Citations (1)
  • Momeny M, .et al. Blockade of nuclear factor-κB (NF-κB) pathway inhibits growth and induces apoptosis in chemoresistant ovarian carcinoma cells, Int J Biochem Cell Biol, 2018, Jun;99:1-9 PMID: 29567488

Chemical Information

Catalog Num A11957
Actions Inhibitor
M. Wt 207.25
Formula C10H9NO2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 19542-67-7
Synonyms Bay-11-7821, Bay 117821, Bay117821,Bay 11-7082, Bay-11-7082, Bay11-7082

Biological Activity

Bay 11-7821 is an irreversible inhibitor of TNF-α-stimulated IκBα phosphorylation.
E2-conjugating enzymes (Cell-free assay) IκBα?phosphorylation (Tumor cells)
N/A10 μM


Solubility (25°C) * In vitro DMSO 41 mg/mL (197.82 mM)
Water <1 mg/mL (<1 mM)
Ethanol 10 mg/mL (48.25 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 15 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 48.25 mL 241.25 mL 482.51mL
0.5 mM 9.65 mL 48.25 mL 96.5 mL
1 mM 4.83 mL 24.13 mL 48.25 mL
5 mM 0.97 mL 4.83 mL 9.65 mL

*The above data is based on the productmolecular weight 207.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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