BAY 80-6946 (Copanlisib)

Catalog No.: A11766

PI3K inhibitor

BAY 80-6946 (Copanlisib)

BAY 80-6946 (Copanlisib) Chemical Structure

CAS NO. 1032568-63-0

BAY 80-6946 is a phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity.

Availability: In stock

Package Price Qty
5 mg
$55.00
10 mg
$80.00
25 mg
$180.00
50 mg
$245.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Shin SM, .et al. Direct targeting of oncogenic RAS mutants with a tumor-specific cytosol-penetrating antibody inhibits RAS mutant-driven tumor growth, Sci Adv, 2020, Jan 15;6(3):eaay2174 PMID: 31998840

Biological Activity

BAY 80-6946 is a phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity.
In vitro DMSO Insoluble
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.82 mL 104.12 mL 208.25 mL
0.5 mM 4.16 mL 20.82 mL 41.65 mL
1 mM 2.08 mL 10.41 mL 20.82 mL
5 mM 0.42 mL 2.08 mL 4.16 mL

*The above data is based on the productmolecular weight 480.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11766
Actions Inhibitor
CAS No. 1032568-63-0
Formula C23H28N8O4
M. Wt 480.2
Solubility DMSO
Purity >98%
Synonyms BAY80-6946, BAY806946
SMILES COC1=C(C=CC2=C1N=C(N3C2=NCC3)NC(=O)C4=CN=C(N=C4)N)OCCCN5CCOCC5
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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