BIBR 1532

Catalog No.: A10140

Telomerase Inhibitor

BIBR 1532

BIBR 1532 Chemical Structure

CAS NO. 321674-73-1

BIBR 1532 is a selective telomerase inhibitor (IC50 values are 93, > 100000 and > 100000 nM for human telomerase, human RNA polymerase I and human RNA polymerase II + III respectively).

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10 mg

Regular Price: $80.00

Special Price $64.00

50 mg

Regular Price: $280.00

Special Price $224.00

100 mg

Regular Price: $380.00

Special Price $304.00

200 mg

Regular Price: $720.00

Special Price $576.00

10mM * 1mL in DMSO

Regular Price: $86.00

Special Price $68.80

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Hosoi T, .et al. Inhibition of telomerase causes vulnerability to endoplasmic reticulum stress-induced neuronal cell death, Neurosci Lett, 2016, Aug 26;629:241-244 PMID: 27443785

Biological Activity

BIBR 1532 is a selective telomerase inhibitor (IC50 values are 93, > 100000 and > 100000 nM for human telomerase, human RNA polymerase I and human RNA polymerase II + III respectively).

Targets
Telomerase (Cell-free assay)
100 nM
In vitro (25°C) DMSO 58 mg/mL (175.03 mM)
Water Insoluble
Ethanol 3 mg/mL (9.05 mM)
In vivo 5% DMSO+corn oil 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.18 mL 150.88 mL 301.75 mL
0.5 mM 6.04 mL 30.18 mL 60.35 mL
1 mM 3.02 mL 15.09 mL 30.18 mL
5 mM 0.6 mL 3.02 mL 6.04 mL

*The above data is based on the productmolecular weight 331.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10140
Actions Inhibitor
CAS No. 321674-73-1
Formula C21H17NO3
M. Wt 331.4
Purity >98%
Synonyms BIBR-1532, BIBR1532
SMILES C/C(=C\C(=O)NC1=CC=CC=C1C(=O)O)/C2=CC3=CC=CC=C3C=C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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