Biotin-PEG6-NHS ester

Catalog No.: A81747
PROTAC Linker
Biotin-PEG6-NHS ester is a polyethylene glycol (PEG)-based linker specifically designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound allows for efficient conjugation to target proteins, facilitating the targeted degradation of specific intracellular proteins. Its biotin moiety enhances affinity for streptavidin or avidin, making it valuable in various biochemical assays and applications in drug discovery. This linker is essential for developing targeted therapeutics utilizing the PROTAC technology.
Grouped product items
Size Price Stock Qty
2mg
$25.00
In stock
5mg
$30.00
In stock
10mg
$50.00
In stock
25mg
$100.00
In stock
50mg
$150.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBiotin-PEG6-NHS ester is a polyethylene glycol (PEG)-based linker specifically designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound allows for efficient conjugation to target proteins, facilitating the targeted degradation of specific intracellular proteins. Its biotin moiety enhances affinity for streptavidin or avidin, making it valuable in various biochemical assays and applications in drug discovery. This linker is essential for developing targeted therapeutics utilizing the PROTAC technology.
Product Information
Catalog NumA81747
FormulaC29H48N4O12S
Molecular Weight676.78
CAS Number2055045-04-8
SMILESO=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCNC(CCCC[C@@H]2SC[C@]([C@]2([H])N3)([H])NC3=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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