Bitopertin (R enantiomer)

Catalog No.: A15022

Glycine reuptake inhibitor

Bitopertin (R enantiomer)

Bitopertin (R enantiomer) Chemical Structure

CAS NO. 845614-12-2

RG1678 (Bitopertin) is a potent and noncompetitive glycine reuptake inhibitor (GlyT1).

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Biological Activity

RG1678 (Bitopertin) is a potent and noncompetitive glycine reuptake inhibitor (GlyT1).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.4 mL 92 mL 184.01 mL
0.5 mM 3.68 mL 18.4 mL 36.8 mL
1 mM 1.84 mL 9.2 mL 18.4 mL
5 mM 0.37 mL 1.84 mL 3.68 mL

*The above data is based on the productmolecular weight 543.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15022
Actions Inhibitor
CAS No. 845614-12-2
Formula C21H20F7N3O4S
M. Wt 543.46
Purity >98%
Synonyms RG1678 (R enantiomer), RG 1678 (R enantiomer), RG-1678 (R enantiomer), RO4917838 (R enantiomer)
SMILES C[[email protected]](C(F)(F)F)OC1=C(C=C(C=C1)S(=O)(=O)C)C(=O)N2CCN(CC2)C3=C(C=C(C=N3)C(F)(F)F)F

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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