Bitopertin

Catalog No.: A15021
Glycine reuptake inhibitor
RG1678 (Bitopertin) is a potent and noncompetitive glycine reuptake inhibitor (GlyT1).
Grouped product items
Product Name Price Stock Qty
Bitopertin 5mg
Special Price $56.00 Regular Price $70.00
In stock
Bitopertin 10mg
Special Price $76.00 Regular Price $95.00
In stock
Bitopertin 50mg
Special Price $312.00 Regular Price $390.00
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Biological Activity
Discription RG1678 (Bitopertin) is a potent and noncompetitive glycine reuptake inhibitor (GlyT1).
Targets
Target Value
Product Information
Catalog Num A15021
Formula C21H20F7N3O4S
Molecular Weight 543.46
CAS Number 845614-11-1
SMILES C[C@@H](C(F)(F)F)OC1=C(C=C(C=C1)S(=O)(=O)C)C(=O)N2CCN(CC2)C3=C(C=C(C=N3)C(F)(F)F)F
Synonyms RG1678, RO4917838, RG-1678, RG 1678, RO-4917838, RO 4917838
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 89 mg/mL (163.76 mM)
Water Insoluble
Ethanol 89 mg/mL (163.76 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.4 mL 92 mL 184.01 mL
0.5 mM 3.68 mL 18.4 mL 36.8 mL
1 mM 1.84 mL 9.2 mL 18.4 mL
5 mM 0.37 mL 1.84 mL 3.68 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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