Boc-Aminooxy-PEG4-azide

Catalog No.: A83570
PROTAC linker
Boc-Aminooxy-PEG4-azide is a PEG-based PROTAC linker that facilitates the synthesis of PROTACs through its unique azide functionality. This compound participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN moieties. Its versatile click chemistry capabilities make it an essential tool for researchers studying targeted protein degradation and other innovative therapeutic approaches.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBoc-Aminooxy-PEG4-azide is a PEG-based PROTAC linker that facilitates the synthesis of PROTACs through its unique azide functionality. This compound participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN moieties. Its versatile click chemistry capabilities make it an essential tool for researchers studying targeted protein degradation and other innovative therapeutic approaches.
Product Information
Catalog NumA83570
FormulaC15H30N4O7
Molecular Weight378.42
CAS Number2100306-64-5
SMILESO=C(OC(C)(C)C)NOCCOCCOCCOCCOCCN=[N+]=[N-]
Useful Calculator

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