Boc-NH-PEG4-azide is a polyethylene glycol (PEG)-based PROTAC linker designed for the synthesis of PROTACs. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, Boc-NH-PEG4-azide can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with donors like DBCO or BCN. Its versatile reactivity makes it a valuable tool in chemical biology and drug discovery research applications.
Boc-NH-PEG4-azide is a polyethylene glycol (PEG)-based PROTAC linker designed for the synthesis of PROTACs. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, Boc-NH-PEG4-azide can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with donors like DBCO or BCN. Its versatile reactivity makes it a valuable tool in chemical biology and drug discovery research applications.
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