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Catalog No.: A15489

HDAC inhibitor


BRD73954 Chemical Structure

CAS NO. 1440209-96-0

BRD73954 is a small molecule inhibitor that potently inhibits both HDAC6 and HDAC8 (IC50s = 36 and 120 nM, respectively).

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Biological Activity

BRD73954 is a small molecule inhibitor that potently inhibits both HDAC6 and HDAC8 (IC50s = 36 and 120 nM, respectively).
36 nM120 nM9 μM>33 μM
In vitro DMSO 49 mg/mL (172.34 mM)
Water Insoluble
Ethanol Warmed: 8 mg/mL (28.13 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.17 mL 175.87 mL 351.74 mL
0.5 mM 7.03 mL 35.17 mL 70.35 mL
1 mM 3.52 mL 17.59 mL 35.17 mL
5 mM 0.7 mL 3.52 mL 7.03 mL

*The above data is based on the productmolecular weight 284.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15489
Actions Inhibitor
CAS No. 1440209-96-0
Formula C16H16N2O3
M. Wt 284.3
Purity >98%
Synonyms BRD-73954, BRD 73954

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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