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Biological Activity
Brefeldin A blocks binding of ADP-ribosylation factor to the Golgi apparatus and inhibits GDP-GTP exchange.
Targets
| ATPase (HCT 116) | ||||
| 0.2 μM |
| In vitro | DMSO | 4 mg/mL (14.26 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 35.66 mL | 178.32 mL | 356.63 mL |
| 0.5 mM | 7.13 mL | 35.66 mL | 71.33 mL |
| 1 mM | 3.57 mL | 17.83 mL | 35.66 mL |
| 5 mM | 0.71 mL | 3.57 mL | 7.13 mL |
*The above data is based on the productmolecular weight 280.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11156 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 20350-15-6 |
| Formula | C16H24O4 |
| M. Wt | 280.4 |
| Purity | >98% |
| Synonyms | Brefeldin-A |
| SMILES | C[[email protected]]1CCC/C=C/[[email protected]@H]2C[[email protected]@H](C[[email protected]]2[[email protected]@H](/C=C/C(=O)O1)O)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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