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Brefeldin A

Catalog No.: A11156

Protein translocation Inhibitor

Brefeldin A

Brefeldin A Chemical Structure

CAS NO. 20350-15-6

Brefeldin A blocks binding of ADP-ribosylation factor to the Golgi apparatus and inhibits GDP-GTP exchange.

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Biological Activity

Brefeldin A blocks binding of ADP-ribosylation factor to the Golgi apparatus and inhibits GDP-GTP exchange.
ATPase (HCT 116)
0.2 μM
In vitro DMSO 4 mg/mL (14.26 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.66 mL 178.32 mL 356.63 mL
0.5 mM 7.13 mL 35.66 mL 71.33 mL
1 mM 3.57 mL 17.83 mL 35.66 mL
5 mM 0.71 mL 3.57 mL 7.13 mL

*The above data is based on the productmolecular weight 280.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11156
Actions Inhibitor
CAS No. 20350-15-6
Formula C16H24O4
M. Wt 280.4
Purity >98%
Synonyms Brefeldin-A
SMILES C[[email protected]]1CCC/C=C/[[email protected]@H]2C[[email protected]@H](C[[email protected]]2[[email protected]@H](/C=C/C(=O)O1)O)O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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