Brilacidin tetrahydrochloride is a defensin mimetic antibiotic that exhibits potent antimicrobial activity against both Gram-positive and Gram-negative bacteria. It demonstrates minimum inhibitory concentrations (MIC90) of 1 μg/mL against Streptococcus pneumoniae and 8 μg/mL against Streptococcus viridans, alongside MIC90 values of 8 μg/mL for Haemophilus influenzae and 4 μg/mL for Pseudomonas aeruginosa. This compound is particularly valuable in microbiological research and the development of novel therapeutic strategies for bacterial infections.
Brilacidin tetrahydrochloride is a defensin mimetic antibiotic that exhibits potent antimicrobial activity against both Gram-positive and Gram-negative bacteria. It demonstrates minimum inhibitory concentrations (MIC90) of 1 μg/mL against Streptococcus pneumoniae and 8 μg/mL against Streptococcus viridans, alongside MIC90 values of 8 μg/mL for Haemophilus influenzae and 4 μg/mL for Pseudomonas aeruginosa. This compound is particularly valuable in microbiological research and the development of novel therapeutic strategies for bacterial infections.
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