Bromo-PEG7-azide is a polyethylene glycol (PEG)-based linker for PROTAC (Proteolysis Targeting Chimeras) synthesis, facilitating targeted protein degradation. This compound features an azide functional group, enabling its use in click chemistry, specifically copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups, making it a versatile tool for researchers in chemical biology and drug development applications.
Bromo-PEG7-azide is a polyethylene glycol (PEG)-based linker for PROTAC (Proteolysis Targeting Chimeras) synthesis, facilitating targeted protein degradation. This compound features an azide functional group, enabling its use in click chemistry, specifically copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups, making it a versatile tool for researchers in chemical biology and drug development applications.
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