C646

Catalog No.: A12815

p300/CBP inhibitor

C646

C646 Chemical Structure

CAS NO. 328968-36-1

C646 is a selective p300/CREB-binding protein (CBP) inhibitor (Ki = 400 nM).

Availability: In stock

Package Price Qty
10 mg
$80.00
25 mg
$160.00
50 mg
$280.00
100 mg
$500.00
10mM * 1mL in DMSO
$95.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Zhifeng Zhang, .et al. XRCC5 cooperates with p300 to promote cyclooxygenase-2 expression and tumor growth in colon cancers, PLoS One, 2017, 12(10): e0186900 PMID: 29049411

Biological Activity

C646 is a selective p300/CREB-binding protein (CBP) inhibitor (Ki = 400 nM).
Targets
p300/CBP (Cell-free assay)
400 nM(Ki)
In vitro (25°C) DMSO 13 mg/mL (29.18 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.45 mL 112.25 mL 224.51 mL
0.5 mM 4.49 mL 22.45 mL 44.9 mL
1 mM 2.25 mL 11.23 mL 22.45 mL
5 mM 0.45 mL 2.25 mL 4.49 mL

*The above data is based on the productmolecular weight 445.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12815
Actions Inhibitor
M. Wt 445.42
Formula C24H19N3O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 328968-36-1
Synonyms C 646, C-646
SMILES CC1=C(C=C(C(=C1)C2=CC=C(O2)/C=C\3/C(=NN(C3=O)C4=CC=C(C=C4)C(=O)O)C)[N+](=O)[O-])C

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy C646 | C646 Supplier | purchase | cost | manufacturer | order | distributor | buy 328968-36-1| 328968-36-1 Supplier | purchase 328968-36-1 | 328968-36-1 cost | 328968-36-1 manufacturer | order 328968-36-1 | 328968-36-1 distributor
Rewards