C646

Catalog No.: A12815
p300/CBP inhibitor
C646 is a selective p300/CREB-binding protein (CBP) inhibitor (Ki = 400 nM).
Grouped product items
Product Name Price Stock Qty
C646 10mg
Special Price $64.00 Regular Price $80.00
In stock
C646 25mg
Special Price $128.00 Regular Price $160.00
In stock
C646 50mg
Special Price $224.00 Regular Price $280.00
In stock
C646 100mg
Special Price $400.00 Regular Price $500.00
In stock
C646 10mM * 1mL in DMSO
Special Price $76.00 Regular Price $95.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's C646 has been cited by 1 publications
  • Zhifeng Zhang, .et al. , PLoS One, 2017, 12(10): e0186900 PMID: 29049411
  • Biological Activity
    Discription C646 is a selective p300/CREB-binding protein (CBP) inhibitor (Ki = 400 nM).
    Targets
    Target Value
    Product Information
    Catalog Num A12815
    Formula C24H19N3O6
    Molecular Weight 445.42
    CAS Number 328968-36-1
    SMILES CC1=C(C=C(C(=C1)C2=CC=C(O2)/C=C\3/C(=NN(C3=O)C4=CC=C(C=C4)C(=O)O)C)[N+](=O)[O-])C
    Synonyms C 646, C-646
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 13 mg/mL (29.18 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 5% DMSO+40% PEG 300+5%Tween 80+ddH2O 1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.45 mL 112.25 mL 224.51 mL
    0.5 mM 4.49 mL 22.45 mL 44.9 mL
    1 mM 2.25 mL 11.23 mL 22.45 mL
    5 mM 0.45 mL 2.25 mL 4.49 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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