Calcium Channel Antagonist 6 (Compound 328) selectively inhibits the voltage-gated calcium channel CaV2.2 with an IC50 value of 0.37 μM. This compound effectively blocks neuron depolarization-induced Ca2+ influx, making it a valuable tool for investigating mechanisms underlying neuropathic pain. Its specificity and potency position it as a promising candidate for further research in pain-related studies.
Calcium Channel Antagonist 6 (Compound 328) selectively inhibits the voltage-gated calcium channel CaV2.2 with an IC50 value of 0.37 μM. This compound effectively blocks neuron depolarization-induced Ca2+ influx, making it a valuable tool for investigating mechanisms underlying neuropathic pain. Its specificity and potency position it as a promising candidate for further research in pain-related studies.
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