Carboxyrhodamine 110-PEG3-Azide is a PEG-based linker designed for the synthesis of PROTACs, facilitating targeted protein degradation. This compound features an azide functional group that permits efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-modified partners. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN derivatives, making it versatile for various click chemistry applications in chemical biology research.
Carboxyrhodamine 110-PEG3-Azide is a PEG-based linker designed for the synthesis of PROTACs, facilitating targeted protein degradation. This compound features an azide functional group that permits efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-modified partners. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN derivatives, making it versatile for various click chemistry applications in chemical biology research.
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