Catalog No.: A14396

Glutaminase inhibitor


CB-839 Chemical Structure

CAS NO. 1439399-58-2

CB-839 an is orally bioavailable inhibitor of glutaminase, with potential antineoplastic activity.

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Beatriz Giesen, .et al. Augmented Therapeutic Potential of Glutaminase Inhibitor CB839 in Glioblastoma Stem Cells Using Gold Nanoparticle Delivery, Pharmaceutics, 2021, Feb 23;13(2):295 PMID: 33672398

Biological Activity

CB-839 an is orally bioavailable inhibitor of glutaminase, with potential antineoplastic activity.
24 nM
In vitro (25°C) DMSO Warmed: 97 mg/mL (169.7 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+corn oil 2 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.5 mL 87.48 mL 174.96 mL
0.5 mM 3.5 mL 17.5 mL 34.99 mL
1 mM 1.75 mL 8.75 mL 17.5 mL
5 mM 0.35 mL 1.75 mL 3.5 mL

*The above data is based on the productmolecular weight 571.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14396
Actions Inhibitor
CAS No. 1439399-58-2
Formula C26H24F3N7O3S
M. Wt 571.57
Purity >98%
Synonyms CB839, CB 839

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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