Cephalochromin is an antibiotic that acts as a specific inhibitor of bacterial fatty acid synthase (FabI). It demonstrates potent inhibitory activity against Staphylococcus aureus and Escherichia coli, with IC50 values of 1.9 µM and 1.8 µM, respectively. Additionally, Cephalochromin is effective against gram-positive methicillin-resistant Staphylococcus aureus (MRSA) and quinolone-resistant S. aureus (QRSA), exhibiting minimum inhibitory concentrations (MIC) in the range of 2-8 µg/mL. This compound is useful in research focused on antibiotic resistance and fatty acid biosynthesis in bacteria.
Cephalochromin is an antibiotic that acts as a specific inhibitor of bacterial fatty acid synthase (FabI). It demonstrates potent inhibitory activity against Staphylococcus aureus and Escherichia coli, with IC50 values of 1.9 µM and 1.8 µM, respectively. Additionally, Cephalochromin is effective against gram-positive methicillin-resistant Staphylococcus aureus (MRSA) and quinolone-resistant S. aureus (QRSA), exhibiting minimum inhibitory concentrations (MIC) in the range of 2-8 µg/mL. This compound is useful in research focused on antibiotic resistance and fatty acid biosynthesis in bacteria.
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