Cercosporamide

Catalog No.: A15362

Mnk2/JAK3 inhibitor

Cercosporamide

Cercosporamide Chemical Structure

CAS NO. 131436-22-1

Cercosporamide, an usnic amide, was originally identified in Cercosporidium henningsii as a host-selective phytotoxin and broad-spectrum antifungal agent and is a potent inhibitor of MAP-kinase interacting kinase-2 (Mnk2; IC50 = 11 nM), JAK3 (IC50 = 31), and Mnk1 (IC50 = 116 nM).

Availability: In stock

Package Price Qty
0.5 mg
$160.00
1 mg
$300.00
2.5 mg
$600.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Cercosporamide, an usnic amide, was originally identified in Cercosporidium henningsii as a host-selective phytotoxin and broad-spectrum antifungal agent and is a potent inhibitor of MAP-kinase interacting kinase-2 (Mnk2; IC50 = 11 nM), JAK3 (IC50 = 31), and Mnk1 (IC50 = 116 nM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.19 mL 150.93 mL 301.86 mL
0.5 mM 6.04 mL 30.19 mL 60.37 mL
1 mM 3.02 mL 15.09 mL 30.19 mL
5 mM 0.6 mL 3.02 mL 6.04 mL

*The above data is based on the productmolecular weight 331.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A15362
Actions Inhibitor
M. Wt 331.28
Formula C16H13NO7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 131436-22-1
Synonyms N/A
SMILES CC(=O)C1=C(C=C2C(C1=O)(C3=C(C=C(C(=C3O2)C(=O)N)O)O)C)O

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