CHDI-390576
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | CHDI-390576, a potent, cell permeable and CNS penetrant class IIa histonedeacetylase (HDAC) inhibitor with IC50s of 54 nM, 60 nM, 31 nM, 50 nM for class IIa HDAC4, HDAC5, HDAC7, HDAC9, respectively, shows >500-fold selectivity over class I HDACs (1, 2, 3) and ~150-fold selectivity over HDAC8 and the class IIb HDAC6 isoform. | ||
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Catalog Num | A18899 |
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Formula | C19H13F4N3O2 |
Molecular Weight | 391.33 |
CAS Number | 1629729-98-1 |
SMILES | O=C(NO)C(C1=CC=CC=C1F)C2=CC=C(C3=NC=C(C(F)(F)F)C=N3)C=C2 |
Synonyms | CHDI390576, CHDI 390576 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2