Clinafloxacin hydrochloride is a potent fluoroquinolone antibiotic that targets DNA gyrase and topoisomerase IV, effectively inhibiting bacterial DNA replication. It demonstrates broad-spectrum antimicrobial activity against both gram-positive and gram-negative bacteria, as well as anaerobic pathogens in vitro. With IC50 values of 0.92 µg/ml and 1.62 µg/ml against S. aureus, this compound is useful for research applications aimed at understanding antibiotic resistance and developing novel antimicrobial therapies.
Clinafloxacin hydrochloride is a potent fluoroquinolone antibiotic that targets DNA gyrase and topoisomerase IV, effectively inhibiting bacterial DNA replication. It demonstrates broad-spectrum antimicrobial activity against both gram-positive and gram-negative bacteria, as well as anaerobic pathogens in vitro. With IC50 values of 0.92 µg/ml and 1.62 µg/ml against S. aureus, this compound is useful for research applications aimed at understanding antibiotic resistance and developing novel antimicrobial therapies.
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