Clindamycin hydrochloride monohydrate is a bacterial inhibitor primarily targeting protein synthesis by binding to the 50S ribosomal subunit. This compound effectively suppresses the expression of virulence factors in Staphylococcus aureus, even at sub-inhibitory concentrations. Clindamycin hydrochloride monohydrate notably decreases the production of key toxins, including Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1), and alpha-haemolysin (Hla), making it a valuable tool in microbiological research and the study of antibiotic resistance mechanisms.
Clindamycin hydrochloride monohydrate is a bacterial inhibitor primarily targeting protein synthesis by binding to the 50S ribosomal subunit. This compound effectively suppresses the expression of virulence factors in Staphylococcus aureus, even at sub-inhibitory concentrations. Clindamycin hydrochloride monohydrate notably decreases the production of key toxins, including Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1), and alpha-haemolysin (Hla), making it a valuable tool in microbiological research and the study of antibiotic resistance mechanisms.
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