Catalog No.
Product Name
Application
Product Information
Citations
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Antibacterial Agent
Deoxyshikonin is an antibacterial agent that exhibits significant activity against methicillin-resistant Staphylococcus aureus (MRSA) and Streptococcus pneumoniae, with a minimum inhibitory concentration (MIC) of 17 μg/mL. It enhances the expression of VEGF-C and VEGF-A mRNA in human microvascular endothelial cells, promotes the interaction of HIF-1α and HIF-1β subunits, and binds to specific DNA sequences associated with HIF. Additionally, Deoxyshikonin demonstrates proangiogenic and antitumor effects by inhibiting colorectal cancer via the PI3K/Akt/mTOR signaling pathway, making it valuable for both antibacterial and cancer research applications. -
Bacterial Inhibitor
Ceftiofur is a cell wall synthesis inhibitor targeting bacterial penicillin-binding proteins (PBPs). It demonstrates bactericidal activity by interfering with the peptidoglycan synthesis in bacterial cell walls, resulting in cell lysis. Additionally, Ceftiofur exhibits anti-inflammatory properties by inhibiting the activation of NF-κB and MAPKs, which decreases the secretion of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6. This makes Ceftiofur a valuable reagent in research investigating bacterial infections and inflammation processes. -
Bacterial Quorum-sensing Signaling Molecule
N-3-oxo-dodecanoyl-L-homoserine lactone is a bacterial quorum-sensing signaling molecule primarily associated with Pseudomonas aeruginosa and Burkholderia cepacia complex. This compound plays a critical role in bacterial communication, regulating gene expression in response to changes in cell density. Additionally, N-3-oxo-dodecanoyl-L-homoserine lactone has been shown to induce interleukin-8 (IL-8) production in human bronchial epithelial cells, making it valuable for research in host-pathogen interactions and inflammatory responses. -
Bacterial Inhibitor
Vasicine, a quinazoline alkaloid derived from Justicia adhatoda, primarily targets bacterial strains as an inhibitor. This compound is known to activate the PI3K/Akt signaling pathway and demonstrates significant antioxidant and anti-inflammatory activities. Its unique biological profile makes Vasicine valuable for research in microbial resistance and inflammation-related studies. -
Bacterial Inhibitor
Vasicine hydrochloride, a quinazoline alkaloid derived from Justicia adhatoda, acts primarily as a bacterial inhibitor. It activates the PI3K/Akt signaling pathway and demonstrates significant antioxidant and anti-inflammatory properties. This compound is valuable for research involving antimicrobial activity and cellular signaling pathways, making it a useful tool for studies in infectious disease and inflammation. -
Antibacterial Agent
Canthin-6-one is an indole alkaloid that serves as an effective antibacterial agent. Its primary mechanism involves the inhibition of bacterial growth, making it valuable for research in antimicrobial applications. Additionally, Canthin-6-one exhibits anti-inflammatory properties, suggesting potential in studies related to inflammation. -
Bacterial Inhibitor
Bavachalcone is a bacterial inhibitor known for its multifaceted biological activities. It induces apoptosis and enhances autophagy in HepG2 cancer cells, contributing to its anticancer potential. Additionally, Bavachalcone demonstrates anti-neuroinflammatory and antidepressant effects through modulation of the NF-κB pathway. It also inhibits osteoclast differentiation by interfering with ERK and Akt signaling pathways, as well as the expression of c-Fos and NFATc1, and shows a significant inhibitory effect on BACE-1 activity in vitro. -
Antibacterial Agent
Desfuroylceftiofur is an antibacterial agent and the predominant microbiologically active metabolite of ceftiofur, retaining an intact β-lactam ring. This compound exhibits in vitro activity against a range of Gram-negative and Gram-positive veterinary pathogens, including common equine pathogens. Desfuroylceftiofur is suitable for research applications focused on respiratory infections in veterinary medicine. -
Bacterial Inhibitor
Lysozyme, also known as Muramidase, is a conserved antimicrobial protein that targets bacterial cell wall peptidoglycan (PG). It exerts a bactericidal effect by hydrolyzing PG, thereby limiting bacterial growth on mucosal surfaces and controlling potential pathogens while preventing dysbiosis through microbiota regulation. Additionally, extracellular lysozyme degrades polymeric PG into soluble fragments, activating NOD receptors in mucosal epithelial cells and stimulating the secretion of chemokines and activating factors by neutrophils and macrophages. This makes lysozyme a valuable reagent for studies involving antimicrobial activity, immune response, and microbiome research. -
Bacterial Inhibitor
Ciclopirox olamine is a synthetic antifungal agent primarily targeting various fungal pathogens. It exhibits a broad spectrum of activity against dermatophytes, yeasts, molds, and multiple Gram-positive and Gram-negative bacteria. In addition to its antibacterial properties, Ciclopirox olamine has demonstrated anticancer and anti-inflammatory effects, making it a valuable reagent for research in superficial mycoses, cancer biology, and inflammation studies. -
Bacterial Inhibitor
Roxithromycin is a semi-synthetic macrolide antibiotic that exerts its antibacterial effects by inhibiting protein biosynthesis at the elongation step through binding to the 50S subunit of the bacterial ribosome. This compound demonstrates broad biological activity, including antimicrobial, antiproliferative, and anti-inflammatory properties. Additionally, Roxithromycin has been shown to inhibit tumor vasculature and alleviate lung injury, making it a valuable reagent for research applications in infectious disease, cancer therapy, and respiratory health. -
Antibacterial/Anticancer Agent
Usnic acid is a secondary metabolite derived from lichens, exhibiting significant antibacterial and anticancer properties. It functions primarily by inhibiting DNA and RNA synthesis, leading to cell cycle arrest and apoptosis in various cancer cell lines. Additionally, usnic acid suppresses RANKL-mediated osteoclast formation and function through downregulation of NFATc1. Its antioxidant and anti-inflammatory effects are attributed to the inhibition of lipid peroxidation and myeloperoxidase activity, making it a valuable reagent for diverse biological research applications. -
Antioxidant/Antibacterial/Anticancer Agent
Carvacrol is a monoterpenic phenol that functions as an antioxidant, antibacterial, and anticancer agent. It has demonstrated the ability to cause cell cycle arrest in the G0/G1 phase, downregulate Notch-1 and Jagged-1, and induce apoptosis in cancerous cells. Carvacrol is frequently utilized in research to investigate its therapeutic effects in various biological systems, alongside its applications in food preservation and cosmetic formulations due to its flavoring and fragrance properties. -
Bacterial Inhibitor
Benzoic acid is an aromatic carboxylic acid that functions as a bacterial inhibitor. It demonstrates significant antimicrobial activity by inhibiting the growth of bacteria and fungi, making it an effective preservative. Benzoic acid is widely utilized in food, beverages, cosmetics, and various research applications to study microbial growth inhibition and preservation techniques. -
Bacterial Inhibitor
Tilmicosin is a macrolide antibiotic and calcium channel antagonist that targets the bacterial ribosome's 50S subunit, effectively inhibiting protein synthesis. It possesses significant antimicrobial activity and is primarily utilized in treating respiratory diseases in livestock, including cattle, sheep, and pigs. Additionally, Tilmicosin exhibits immunomodulatory and anti-inflammatory properties, making it a valuable reagent in veterinary medicine research. -
Antibacterial Agent
Tilmicosin phosphate is a macrolide antibiotic that primarily targets the 50S subunit of bacterial ribosomes, effectively inhibiting protein synthesis. This compound exhibits antibacterial properties, making it particularly useful for treating respiratory infections in livestock, including cattle, sheep, and pigs. Additionally, Tilmicosin phosphate demonstrates immunomodulatory and anti-inflammatory activities that may enhance its therapeutic efficacy in veterinary applications. -
Antibacterial Agent
Chlorhexidine diacetate is a cationic antimicrobial agent that primarily targets microbial cell membranes. Its mechanism involves non-specific binding to membrane phospholipids, leading to structural disruption and leakage of cellular contents. Chlorhexidine diacetate exhibits broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria, making it valuable for applications in microbiology and infection control. Additionally, it can adversely affect membrane permeability, resulting in protein precipitation and metabolic disturbances, which contribute to rapid microbial growth inhibition and induction of cell death. -
Antibacterial Agent
5,7-Dihydroxy-4-methylcoumarin is a coumarin derivative known for its antibacterial properties. This compound exhibits significant antifungal and antibacterial activities, making it valuable for research in microbial inhibition. Its potential applications include studying mechanisms of action against various pathogens and developing new antimicrobial agents. -
Antibacterial Agent
D-Gluconic acid calcium hydrate is a carboxylic acid known for its antibacterial and chelating properties. It plays a significant role in inhibiting bacterial growth and is commonly used in various biomedical and pharmaceutical research applications. Its ability to complex with metal ions makes it valuable for studies involving metal ion regulation and antimicrobial effectiveness. -
Bacterial Inhibitor
Sodium citrate dihydrate is a bacterial inhibitor that acts by disrupting cellular processes in bacteria. This compound exhibits antibacterial, anti-tumor, and antioxidant activities, demonstrating potential in both microbial and cancer research applications. It can be utilized as a cosolvent or buffer in various biochemical assays, facilitating enhanced stability and solubility of target compounds. -
Anti-Bacterial Agent
Cephemimycin is an antibacterial agent that exhibits modest activity against bacterial and fungal pathogens. This compound is primarily utilized in research focused on antimicrobial resistance and the development of new antibiotic therapies. Its spectrum of activity may provide insights into the mechanisms of bacterial inhibition and inform further studies in pharmacology and microbiology. -
Anti-Bacterial/Fungal Agent
Aspochalasin A is an anti-bacterial and anti-fungal agent that targets microbial cell wall synthesis. It demonstrates significant inhibitory activity against a range of pathogenic bacteria and fungi, making it a valuable tool in the study of antimicrobial resistance. Research applications include examining its efficacy in infection models and investigating potential therapeutic uses in treating bacterial and fungal infections. -
Anti-Bacterial/Fungal Agent
Clavalanine is an anti-bacterial and anti-fungal agent that specifically inhibits a range of bacterial and fungal strains. Its mechanism of action involves disruption of microbial cell wall synthesis, leading to cell lysis and death. Clavalanine is utilized in research applications focused on investigating and combating infectious diseases caused by resistant microbial strains. -
Antibacterial Agent
(9Z)-9,17-Octadecadiene-12,14-diyne-1,11,16-triol is a natural product primarily recognized for its antibacterial properties. It exhibits significant activity against Bacillus subtilis and Pseudomonas fluorescens, as well as antifungal activity against Cladosporium cucumerinum and molluscicidal effects on Biomphalaria glabrata. Additionally, this compound serves as a valuable click chemistry reagent due to its alkyne functionality, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, facilitating diverse applications in chemical biology and pharmaceutical research. -
Antibacterial Agent
SMTP-0 (ent-Stachybotrin B) is an antibacterial agent derived from Stachybotrys microspora. While it is an enantiomer of Stachybotrin B and a member of the SMTP family, it does not exhibit plasminogen modulation activity. SMTP-0 demonstrates notable antibacterial and antifungal properties, making it a valuable tool for research into infectious diseases. -
Antibacterial Agent
Cuevaene A is an antibacterial agent with demonstrated activity against Gram-positive bacteria, notably Bacillus subtilis (ATCC 11060). Additionally, it exhibits modest antifungal properties against various fungal strains, including Fusarium verticillioides (S68) and Rhizoctonia solani (GXE4). This compound is useful for research applications aimed at investigating antibacterial and antifungal mechanisms, as well as exploring potential therapeutic options in microbial infections. -
Antibacterial Agent
Antifungal agent 85 (compound 24f) functions as a potent antibacterial agent, demonstrating minimum inhibitory concentration (MIC) values ranging from 2.5 to 10 μM against a variety of Gram-positive bacteria. This compound is valuable for research applications focusing on bacterial infections and the development of new antimicrobial therapies. -
Anti-Bacterial Agent
Bagremycin B is an antibacterial agent derived from the Streptomyces sp. Tu 4128 strain. It exhibits weak activity against Gram-positive bacteria, as well as the fungi Saccharomyces cerevisiae and Candida albicans. This compound is primarily utilized in research applications focusing on the inhibition of bacterial and fungal growth, contributing to the understanding of antimicrobial mechanisms and the development of new therapeutic agents. -
Antibacterial Agent
Antibacterial agent 229 is a potent antibacterial compound that targets bacterial membranes and DNA. It exhibits significant antibacterial and antifungal activity by disrupting the integrity of bacterial membranes and intercalating into DNA structures. Furthermore, it inhibits topoisomerase IV with an IC50 value of 10.88 µM, making it a valuable tool for research applications in microbiology and drug development. -
Antibacterial Agent
N,O-Diacetyltyramine is an antibacterial agent that exhibits cytotoxic properties. It is derived from the actinomycete Pseudonocardia endophytica VUK-10 and demonstrates activity against both Gram-positive and Gram-negative bacteria, as well as fungi. Additionally, N,O-Diacetyltyramine has been shown to be cytotoxic to various cancer cell lines, including MDA-MB-231, HeLa, MCF-7, and OAW-42, making it a promising candidate for research in antimicrobial and anticancer applications. -
Antibacterial Agent
Aurachin C is an isoprenoid quinoline alkaloid that functions primarily as a selective inhibitor of terminal oxidases. It exhibits significant antibacterial, antiplasmodial, and antifungal properties, making it a valuable compound for research in infectious disease models. Its mechanism of action and broad-spectrum activity render Aurachin C a useful tool for investigating microbial resistance and developing new antimicrobial therapies. -
Anti-Bacterial Agent
Bagremycin A is an anti-bacterial agent derived from the Streptomyces sp. Tu 4128 strain. It exhibits modest activity against Gram-positive bacteria, as well as the yeast Saccharomyces cerevisiae and the pathogenic fungus Candida albicans. This reagent is utilized in research applications aimed at exploring bacterial resistance mechanisms and the development of novel antimicrobial strategies. -
Antibacterial Agent
1-Methyl-4-nitroimidazole is an antibacterial agent that functions primarily through reduction by bacterial nitroreductases, leading to the generation of toxic derivatives. These derivatives induce DNA damage and inhibit bacterial nucleic acid synthesis, while also producing toxic superoxides that promote bacterial cell death. This compound demonstrates moderate in vitro activity against both bacterial and fungal pathogens and is applicable in research focused on skin infections, purulent infections, and urinary tract infections. -
Antibacterial Agent
Cuevaene B is an antibacterial agent isolated from the gdmAI-disrupted strain of Streptomyces sp. LZ35. It exhibits moderate activity against Gram-positive bacteria, such as Bacillus subtilis, and demonstrates modest antifungal properties against fungi including Fusarium verticillioides and Rhizoctonia solani. This compound is applicable in studies investigating bacterial and fungal inhibition, contributing to the development of novel antimicrobial agents. -
Antibacterial Agent
Rugulosin is a crystalline compound derived from Penicillium rugulosum, exhibiting potent antibacterial properties. This agent demonstrates selective activity against a variety of bacterial strains while also displaying moderate antifungal effects. Its unique biological activity makes Rugulosin a valuable tool for research in microbial biology and the development of new antibacterial therapies. -
Antibacterial/Fungicidal Agent
Sepiumol A is a polyphenolic compound derived from the bark of Periploca sepium Bunge, functioning as an antibacterial and antifungal agent. This compound demonstrates notable biological activity against various bacterial and fungal strains, making it a valuable resource in microbiological research. Additionally, Sepiumol A has potential applications in the formulation of e-cigarette liquids, where it may help mitigate undesirable sweetness and greasiness while enhancing microbial safety. -
Bacterial Metabolite
(–)-Mycousnine is a microbial metabolite and derivative of Usnic Acid, with notable antibacterial and antifungal properties. It demonstrates activity against Gram-positive bacteria, including Bacillus subtilis, Kocuria rhizophila, and Staphylococcus aureus, with minimum inhibitory concentrations (MICs) of 4, 8, and 4 µg/mL, respectively. In contrast, it exhibits limited effectiveness against Gram-negative bacteria such as Escherichia coli, Salmonella typhimurium, and Klebsiella pneumoniae. Additionally, (–)-Mycousnine is effective against fungi, including Trichophyton mentagrophytes, Trichophyton rubrum, and Candida albicans, with MICs of 25, 25, and 100 µg/mL, respectively. This compound is suitable for research in antimicrobial drug development and fungal infection studies. -
Antibacterial Drug
Antibacterial agent 129 is an oxetanyl-quinoline derivative that exhibits potent antibacterial activity targeting Pseudomonas mirabilis and Bacillus subtilis, with minimum inhibitory concentrations (MICs) of 31.25 μM and 31.5 μM, respectively. Additionally, it demonstrates significant antifungal activity against Aspergillus niger, also with an MIC of 31.25 μM. Notably, Antibacterial agent 129 displays excellent antimycobacterial properties, with an MIC of 57.73 μM against Mycobacterium tuberculosis H37Rv. This compound can be utilized in pharmaceutical research to explore new antibacterial and antifungal therapies. -
Antibacterial Agent
8-Acetyl-7-hydroxycoumarin is a coumarin derivative that exhibits significant antibacterial and antifungal activities. This compound targets bacterial cell membranes, disrupting their integrity and leading to cell death. It is valuable for research in the development of novel antimicrobial agents and studying microbial resistance mechanisms. -
Antibacterial Agent
A-26771B is an antibacterial agent derived from Penicillium turbatum. It demonstrates moderate antimicrobial activity against Gram-positive bacteria, mycoplasma, and fungi. Additionally, A-26771B inhibits potassium-dependent ATPase in rat liver mitochondria, making it useful for research applications focused on microbial resistance and mitochondrial function. -
Antibacterial Agent
Isodihydroauroglaucin is a fungal metabolite that acts as an antibacterial agent. It exhibits significant antibacterial activity, making it a valuable tool in the study of microbial infections and antibiotic resistance. Researchers can utilize Isodihydroauroglaucin to explore its potential applications in developing new antimicrobial therapies. -
Antibacterial Agent
Antibacterial Agent 232 (compound Y41) is a potent antibacterial compound that targets bacterial cell membranes. It exerts its biological activity by inducing cell peroxidation, leading to disruption of membrane integrity. This reagent is applicable in research exploring antibacterial mechanisms and developing new therapeutic strategies against resistant bacterial strains. -
Bacterial
Fenticonazole is an imidazole derivative that targets bacterial and fungal organisms. It exhibits significant antibacterial and antifungal activity, making it a valuable compound for the study of mixed vaginitis. This reagent is useful in exploring the efficacy of treatments against infections caused by both bacteria and fungi. -
Antimycobacterial Agent
Antituberculosis agent-6 is a potent antimycobacterial agent targeting Mycobacterium tuberculosis. It demonstrates significant activity with a minimum inhibitory concentration (MIC) of 3.49 μM. Additionally, Antituberculosis agent-6 exhibits notable antifungal efficacy against Aspergillus niger, with an MIC of 62.50 μM. The compound also shows high gastrointestinal absorption, making it a valuable candidate for further research in tuberculosis and fungal infections. -
Bacterial/Fungal Inhibitor
Pyruvic acid semicarbazone is a bacterial and fungal inhibitor. This compound demonstrates significant biological activity against various microbial strains, making it a valuable tool for investigating anti-infective agents. Additionally, pyruvic acid semicarbazone has potential applications in cancer research and plant growth regulation studies. -
Antibacterial Agent
NK 1971 is an antibacterial agent that exhibits promising antifungal activity. This compound has been studied for its effects on microbial infections and may impact neurological functions, potentially leading to decreased motor skills and seizures in animal models. Its diverse biological activity makes it a valuable tool for research in microbial pathogenesis and therapeutic interventions. -
Antibacterial Agent
RMG8-8 is an antibacterial agent with demonstrated efficacy against Cryptococcus neoformans, exhibiting an IC50 of 1.56 μg/mL. This compound is valuable for research focused on fungal infections and therapeutic development. Its potent activity provides a useful tool for screening and evaluating new antifungal strategies. -
Anticancer/antibacterial Agent
Antioxidant/anticancer agent 1 is a pyrimidine-derivatized Schiff base derived from pyrimidine hydroxy-1-naphthaldehyde, targeting multiple biological pathways. This compound exhibits significant antibacterial, antioxidant, antifungal, and anticancer activities, making it a valuable reagent for diverse research applications. Its multifaceted biological properties position it as a candidate for further investigation in cancer and infectious disease studies. -
Anti-bacterial Agent
(±)-Lomatin, a coumarin-type secondary metabolite derived from Coleonema album, exhibits significant antibacterial activity. It is primarily researched for its efficacy against bacterial, mycobacterial, and fungal infections. This compound serves as a valuable tool in investigating microbial pathogenesis and the development of novel antimicrobial therapies. -
Antibacterial Agent
Bacimethrin (NSC 66577) is an antibacterial agent that acts as an antagonist of thiamin biosynthesis. This compound effectively inhibits the growth of various bacteria and yeast, making it a valuable tool in microbiological research. Its application extends to studies investigating bacterial resistance mechanisms and the development of new antibacterial therapies.
