• Sign In
  • FAQ
  • Create an Account
Currency
USD currency flagUSD
Toggle Nav
My Cart
Menu
Account
Settings
Currency
USD currency flagUSD

Cobiprostone

Catalog No.: A66539
Type-2 Chloride Channel Activator
Cobiprostone is a type-2 chloride channel activator known for its protective effects against NSAID-induced cellular damage. It effectively prevents Indomethacin-induced depolarization of mitochondrial membrane potential and reverses subsequent loss of membrane integrity. This compound is valuable for research focused on mitochondrial function and cellular responsiveness to ion channel modulation.
Cobiprostone 333963-42-1 Type-2 Chloride Channel Activator
Grouped product items
Size Stock
5mg
10mg
50mg
Bulk Size
Bulk Discount
Bulk Inquiry
Notify me when the price drops
Notify me when this product is in stock
Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCobiprostone is a type-2 chloride channel activator known for its protective effects against NSAID-induced cellular damage. It effectively prevents Indomethacin-induced depolarization of mitochondrial membrane potential and reverses subsequent loss of membrane integrity. This compound is valuable for research focused on mitochondrial function and cellular responsiveness to ion channel modulation.
Product Information
Catalog NumA66539
FormulaC21H34F2O5
Molecular Weight404.49
CAS Number333963-42-1
SMILESO=C(O)CCCCCC[C@H]([C@]1([H])[C@]2([H])O[C@@](O)(C(F)(F)C[C@@H](C)CC)CC1)C(C2)=O
SynonymsSPI 8811
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

Membrane Transporters-Ion Channels > Chloride Channels