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Coformycin

Catalog No.: A46684
Antibiotic
Coformycin is a nucleoside antibiotic that primarily inhibits adenosine deaminase (ADA), an enzyme crucial for purine metabolism. This compound exhibits significant anti-tumor and anti-bacterial properties, making it valuable for research in cancer treatment and infectious disease. Coformycin's ability to modulate adenosine levels underscores its potential in therapeutic applications related to cellular proliferation and immune response.
Coformycin 11033-22-0 Antibiotic
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCoformycin is a nucleoside antibiotic that primarily inhibits adenosine deaminase (ADA), an enzyme crucial for purine metabolism. This compound exhibits significant anti-tumor and anti-bacterial properties, making it valuable for research in cancer treatment and infectious disease. Coformycin's ability to modulate adenosine levels underscores its potential in therapeutic applications related to cellular proliferation and immune response.
Product Information
Catalog NumA46684
FormulaC11H16N4O5
Molecular Weight284.27
CAS Number11033-22-0
SMILESO[C@H]1C2=C(NC=NC1)N(C=N2)[C@H]3[C@H](O)[C@H](O)[C@H](O3)CO
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Microbiology > Antifection > Antibiotic