Concanamycin B is a macrolide antibiotic that selectively inhibits vacuolar-type H+-ATPases, with an IC50 value of 5 nM. This inhibition disrupts proton gradient formation, leading to membrane potential alterations in target cells. Concanamycin B is widely used in research to study cellular ion homeostasis, lysosomal function, and autophagy processes.
Concanamycin B is a macrolide antibiotic that selectively inhibits vacuolar-type H+-ATPases, with an IC50 value of 5 nM. This inhibition disrupts proton gradient formation, leading to membrane potential alterations in target cells. Concanamycin B is widely used in research to study cellular ion homeostasis, lysosomal function, and autophagy processes.
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